Month: July 2021

Investigation of the biological indicator for vaccine efficacy against highly pathogenic avian influenza (HPAI) H5N1 virus challenge in mice and ferrets.
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Investigation of the biological indicator for vaccine efficacy against highly pathogenic avian influenza (HPAI) H5N1 virus challenge in mice and ferrets.

To analyze the organic indicator for vaccine efficacy in opposition to HPAI H5N1 virus problem of various clades, two inactivated whole-virus H5N1 vaccines containing the hemagglutinin (HA) and neuraminidase (NA) genes of both clade 2.2 A/EM/Korea/W149/06 (RgKoreaW149/06 x PR8) or clade 2.5 A/Ck/Korea/ES/03 (RgKoreaES223N/03XPR8) virus within the background of A/PR/8/34 (H1N1) had been generated by […]

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Prime-boost vaccination with a fowlpox vector and an inactivated avian influenza vaccine is highly immunogenic in Pekin ducks challenged with Asian H5N1 HPAI.
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Prime-boost vaccination with a fowlpox vector and an inactivated avian influenza vaccine is highly immunogenic in Pekin ducks challenged with Asian H5N1 HPAI.

The efficacy of various vaccination schedules was evaluated in 17-day-old Pekin geese utilizing an experimental inactivated entire virus vaccine based mostly on the H5N9 A/hen/Italy/22A/98 isolate (H5N9-It) and/or a fowlpox recombinant (vFP-H5) expressing an artificial HA gene from an Asian H5N1 isolate (A/hen/Indonesia/7/2003). Full safety towards scientific indicators and shedding was induced by the totally […]

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