Author: Lieven

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Tedizolid

Introduction: Tedizolid phosphate is an oxazolidinone approved for the treatment of acute bacterial infections of the skin and skin structure (ABSSSI) and active against methicillin-resistant Staphylococcus aureus. Objectives: The objective of this article was to review the evidence for the efficacy and safety of tedizolid phosphate for the treatment of ABSSSI. Review of evidence: Approval […]

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Istaroxime hydrochloride

General description: Product group: Chemicals Category: Other CAS No: 374559-48-5 Properties: Purity:> 98% Molecular Formula: C21H33ClN2O3 Molecular weight: 396.95 UNSPSC: 12352200 Scientific information: Istaroxime Hcl (PST-2744 Hcl) is a positive inotropic agent that mediates its action by inhibiting sodium / potassium adenosine triphosphatase (Na + / K + ATPase). IC50 value: 0.43 +/- 0.15 uM […]

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Brassinolide

Resume We conducted field and pot experiments to investigate the effects of brassinolide on 1-year-old Robinia pseudoacacia L. seedlings. In the field experiment, the roots of the seedlings were soaked in brassinolide solutions containing 0–0.4 mg / l of pure brassinolide before planting. Seedling survival and growth were determined 8 months later. The results showed […]

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Ruxolitinib (INCB018424)

Background Ruxolitinib dihydrochloride is a specific inhibitor of Janus-associated kinase (JAK1 and JAK2). Ruxolitinib is a small molecular with the formula C17H21N6O4P and a molecular weight of 404. Ruxolitinib phosphate is a cyclopentyl propionitrile derivative competitive with administered ATP and shows inhibitory activity on JAK1 and JAK2. Ruxolitinib inhibits phosphorylation of JAK1 / 2, STAT5, […]

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PCI-32765, BTK Inhibitor

Resume Small molecule drugs that target the B-cell antigen receptor (BCR) signalosome show clinical efficacy in the treatment of B-cell non-Hodgkin lymphoma. These agents, including Bruton’s tyrosine kinase (BTK) inhibitor PCI -32765, show an unexpected response in patients with chronic lymphocytic leukemia (CLL): a rapid and sustained reduction in lymphadenopathy accompanied by transient lymphocytosis, which […]

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A Systematic Evaluation of Measures Against Highly Pathogenic Avian Influenza (HPAI) in Indonesia.
Camel

A Systematic Evaluation of Measures Against Highly Pathogenic Avian Influenza (HPAI) in Indonesia.

Over the previous years, many alternative management measures have been applied to forestall HPAI an infection. The nationwide plan with quite a few measures result in issues when it comes to prioritization and funds allocation. Our research goals are to (i) set up a list of measures on HPAI management in Indonesia because the first […]

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Qualitative risk assessment of transmission pathways of highly pathogenic avian influenza (HPAI) virus at live poultry markets in Dhaka city, Bangladesh
Yeast

Qualitative risk assessment of transmission pathways of highly pathogenic avian influenza (HPAI) virus at live poultry markets in Dhaka city, Bangladesh

Evaluation of environmental samples obtained from the Dwell Poultry Markets (LPMs) of Dhaka Metropolis, Bangladesh, has revealed that the very best diploma of prevalence of extremely pathogenic avian influenza A (HPAI, H5N1), in addition to different subtypes of the LPAI virus, poses the believable danger of transmission of those viruses between human and poultry species. […]

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